A recent study published in the Journal of Endocrinology found that Vitamin D3 promotes the expression of pro-muscle building growth factors while inhibiting the expression of myostatin, the only known negative regulator of muscle mass. Vitamin D3 is a potent secosteroid pro-hormone that is acquired either from direct sunlight or dietary consumption. For years Vitamin D has been associated with bone mineralization, but now scientist are increasingly discovering numerous physiological processes where Vitamin D plays a key role. During the study, researchers found that Vitamin D3 increased IGF2 and follistatin growth factors, while inhibiting the expression of myostatin. Researchers also discovered vitamin D3 receptors expressed in muscle tissue, particularly in fast-twitch type 2 fibers revealing the reason for declining levels of Vitamin D3 in the elderly. (Endocrinology, Garcia et al. 152 (8):2976). Leah A Garcia, Keisha K. King, Monica G. Ferrini, Keith C Norris and Jorge N. Artaza.
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